Cattle
Chanazine 2% is given by intramuscular injection. The dose-rate is 0.05-0.3 mg/kg bodyweight (0.25-1.5 ml/100 kg), according to the degree of sedation required. Very fractious animals may require the higher dose rates not exceeding 0.3 mg/kg (Dose rate 4)
Dose | mg/kg | mg/50kg | ml/50kg |
1. | 0.05 | 2.5 | 0.12 |
2. | 0.1 | 5.0 | 0.25 |
3. | 0.2 | 10.0 | 0.5 |
4. | 0.3 | 15.0 | 0.75 |
Dose 1: | Sedation with slight decrease in muscle tone. |
Dose 2: | Sedation, marked decrease in muscle tone and some analgesia. The animal usually remains standing. |
Dose 3: | Deep sedation, further decrease in muscle tone and a useful degree of analgesia. The animal lies down. |
Dose 4: | Very deep sedation, a profound decrease in muscle tone and a useful degree of analgesia. The animal lies down. |
Animals should not be disturbed until Chanazine has taken its full effect. Onset of effect is usually seen within 15 minutes and effects persist for approximately 45 - 60 minutes depending on the dosage rate used. Induction and recovery are smooth. Local anaesthetics should be used in combination with Chanazine where major surgical treatment is carried out.
Horses
Chanazine 2% is given by slow intravenous injection. Dosage depends upon the degree of sedation required and the response of the animal, and is 0.6 - 1 mg/kg (3–5 ml/100 kg) bodyweight. Nervous or excitable horses may require higher doses. Older horses and those having undergone severe physical exertion before treatment should receive the lowest dose rate. The horse does not usually become recumbent after administration and light to deep sedation with variable degree of analgesia is obtained. Effects are usually seen within 5 minutes and persist for approximately 20 minutes. Chanazine 2% may be employed in the horse as a premedication to barbiturate anaesthesia or in combination with regional or local anaesthesia.
Dogs
Chanazine 2% is administered intramuscularly at dose rates of 1–3 mg/kg (0.05–0.15 ml/kg bodyweight). For painful procedures it may be used in combination with a local anaesthetic.
Premedication with atropine may be desirable in some cases. Chanazine 2% is synergistic with the barbiturates and reduces the dosage of the latter by approximately one half.
Cats
Chanazine 2% is administered intramuscularly at a dose rate of 3 mg/kg (0.15 ml/kg) bodyweight. Premedication with atropine may occasionally be desirable.