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Dosage and administration
For single intramuscular injection.
Atipamezole hydrochloride is administered 15-60 min after medetomidine or dexmedetomidine hydrochloride administration.
Dogs: the intramuscular atipamezole hydrochloride dose [in µg] is five times that of the previous medetomidine hydrochloride dose or ten times that of the dexmedetomidine hydrochloride dose. Due to the 5-fold higher concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml and the 10-fold higher concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, an equal volume of each preparation is required.
Dosage Example: Dogs
Medetomidine 1 mg/ml solution for injection dosage
Revertor 5 mg/kg solution for injection for dogs dosage
0.04 ml/kg body weight (bw)
0.04 ml/kg bw,
ie 40 microgram/kg bw
ie 200 microgram/kg bw
Dexmedetomidine 0.5 mg/ml solution for injection dosage
Revertor 5 mg/ml solution for injection for dogs dosage
0.04 ml/kg body weight (bw)
0.04 ml/kg bw
i.e. 20 µg/kg bw
i.e. 200 µg/kg bw
Cats: the intramuscular atipamezole hydrochloride dose [in µg] is two-and-a-half times that of the previous medetomidine hydrochloride dose or five times that of the dexmedetomidine hydrochloride dose. Due to the 5-fold higher concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml and the 10-fold higher concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, half the volume of the product to that of the previously administered medetomidine or dexmedetomidine should be given.
Dosage Example: Cats
Medetomidine 1 mg/ml injection dosage
Revertor 5 mg/ml injection for cats dosage
0.08ml/kg bodyweight (bw)
0.04ml/kg bw,
i.e. 80 µg/kg bw
i.e 200 µg/kg bw
Dexmedetomidine 0.5 mg/ml injection dosage
Revertor 5 mg/ml injection for cats dosage
0.08 ml/kg body weight (bw),
i.e. 40 µg/kg bw
0.04 ml/kg bw,
i.e. 200 µg/kg bw
The recovery time is shortened to approximately 5 minutes. The animal becomes mobile after approximately 10 minutes after administration of the product.