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Date: Saturday, May 18, 2024 16:18

Release 5.97
Lignol® 2.0% w/v Solution for Injection
 
Species: Horses and other equidae, Cats, Dogs
Therapeutic indication: Pharmaceuticals: Neurological preparations: Local anaesthetics
Active ingredient: Adrenaline, Lidocaine Hydrochloride (Lignocaine Hydrochloride)
Product:Lignol® 2.0% w/v Solution for Injection
Product index: Lignol 2.0% w/v Solution for Injection
Withdrawal notes: Horse meat: Zero days.
Incorporating:
Qualitative and quantitative composition
Active ingredients:
Lidocaine hydrochloride / Lignocaine hydrochloride 2.0% w/v
Adrenaline acid tartrate* /Epinephrine acid tartrate 0.00198% w/v
*Including a 10% manufacturing overage
Pharmaceutical form
Solution for injection. Sterile, aqueous solution.
Clinical particulars
Target species
Cats, dogs and horses.
Indications for use
A local anaesthetic agent for regional nerve block, paravertebral nerve block and infiltration anaesthesia, for use in cats, dogs and horses.
Contraindications
Do not use in cardiac or hepatic insufficiency.
Special precautions for use in animals
Do not administer by intravenous injection.
Do not use for more than one induction of anaesthesia in any 24 hours.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Following accidental self injection or ingestion, seek medical advice taking the vial with you. Following eye contamination or excessive skin contact, irrigate/wash thoroughly with cold running water. Seek medical advice if irritation persists.
Use during pregnancy and lactation
Use with caution in pregnant animals.
Amounts to be administered and administration route
For local nerve block, by subcutaneous injection.
Cat infiltration
1 ml
Dog infiltration
1-2 ml
Horse infiltration
50 ml max
For paravertebral block
Up to 10 ml each nerve
Overdose
Local anaesthetics may have systemic adverse effects as a result of the raised plasma concentrations which occur when the rate of absorption exceeds the rate of breakdown. Toxicity causes excitation of the central nervous system, which may be followed by systemic depression leading to coma. Convulsions may be controlled with Diazepam.
Withdrawal periods
Horse meat: zero days.
Pharmacological particulars
Pharmacotherapeutic group: Lidocaine, combinations.
ATCvet code: QN01BB52
Pharmacodynamic properties
Lidocaine is a local anaesthetic of the amide type, used both by injection and for local application to mucous membranes.
Pharmacokinetic properties
Lidocaine has rapid onset of action when injected and spreads rapidly through surrounding tissues. The speed of onset and duration of action of Lidocaine may be increased by the addition of a vasoconstrictor.
Adrenaline is added to local anaesthetics, such as Lidocaine hydrochloride, to slow diffusion and limit absorption as it constricts arterioles and capillaries, so prolonging the duration of the effect and lessening the danger of toxicity.
Pharmaceutical particulars
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after first opening the immediate packaging: 28 days.
Special precautions for storage
Do not store above 25°C.
Discard unused material.
Immediate packaging
100 ml neutral amber glass vial fitted with a red rubber plug and an aluminium seal, containing a sterile, aqueous solution.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Marketing Authorisation Holder (if different from distributor)
Dechra Limited, Snaygill Industrial Estate, Keighley Road, Skipton, North Yorkshire, BD23 2RW, United Kingdom.
Marketing Authorisation Number
Vm 10434/4028
Significant changes
Date of the first authorisation or date of renewal
31 August 1993
Date of revision of the text
September 2016
Any other information
For animal treatment only. To be supplied only on veterinary prescription. Keep out of the sight and reach of children.
Legal category
Legal category: POM-VPS
GTIN
GTIN description:Lignol 2.0% w/v Solution for Injection:
GTIN:05055031410576