NOAH Compendium

Printed from NOAH Compendium (https://www.noahcompendium.co.uk). (c) Copyright NOAH Compendium 2024. All Rights Reserved.
Date: Saturday, May 18, 2024 15:16

Release 4.52
Vetivex® 18 (Sodium Chloride 0.18% w/v and Glucose 4% w/v Intravenous Solution for Infusion BP (Vet))
Species: Cats, Cattle, Dogs, Horses and other equidae
Therapeutic indication: Pharmaceuticals: Dietary supplements and fluid metabolites: Oral rehydration and fluid replacements
Active ingredient: Glucose Monohydrate, Sodium Chloride
Product:Vetivex® 18 (Sodium Chloride 0.18% w/v and Glucose 4% w/v Intravenous Solution for Infusion BP (Vet))
Product index: Vetivex 18 (Sodium Chloride 0.18% w/v and Glucose 4% w/v Intravenous Solution for Infusion BP (Vet))
Cattle - milk: Zero hours
Cattle - meat: Zero days
Withdrawal notes: Horse meat: Zero days.
Incorporating:
Qualitative and quantitative composition
Active substances:
Sodium Chloride 0.18 % w/v
Glucose monohydrate 4.4% w/v
(equivalent to anhydrous glucose 4.0% w/v)
Approximate ionic content in millimoles per litre:
Sodium 30 mmol/L
Chloride 30 mmol/L
Each one litre provides approximately 150 kcal.
Pharmaceutical form
Solution for infusion. Clear, colourless solution.
Clinical particulars
Target species
Cattle, calves, horses, dogs and cats.
Indications for use
This product is administered by intravenous infusion for maintenance therapy of dehydration in cattle, calves, horses, dogs and cats. It should be used once the underlying fluid balance has been restored.
Special precautions for use in animals
Sodium overload may occur in animals with cardiac or renal impairment. It should be noted that sodium excretion may be impaired post-surgery/trauma.
Administration of this product to diabetic animals must be conducted with extreme caution.
The solution should ideally be warmed to approximately 37°C prior to the administration of large volumes, or if the administration rate is high, in order to avoid hypothermia.
This product should not be used for prolonged periods of time unless there is continuing excessive loss of electrolytes, as it may provoke hypokalaemia.
Adverse reactions
There is a risk of thrombosis with intravenous infusion.
Excessive infusion rates can cause restlessness, moist lung sounds, tachycardia, tachypnoea, nasal discharge, coughing, vomiting and diarrhoea.
Use during pregnancy and lactation
Use under veterinary supervision.
Amounts to be administered and administration route
Intravenous administration.
Do not use unless the solution is clear, free from visible particles and the container is undamaged.
The product does not contain an antimicrobial preservative. It is intended for single use only and any unused contents should be discarded.
The solution should ideally be warmed to approximately 37°C prior to administration.
The volume and rate of infusion will depend upon the clinical condition, existing deficits of the animal, maintenance needs and continuing losses.
Generally, recommended dose for maintenance therapy: 50 ml per kg body weight per day.
The infusion rate should be decreased in the presence of cardiac and pulmonary disease.
The maximum recommended infusion rate is 12 ml/kg/hour, otherwise it is liable to cause glycosuria and osmotic diuresis.
Overdose
Monitor fluid output and blood glucose. The administration of a diuretic may be necessary.
Withdrawal periods
Meat and offal: Zero days
Milk: Zero hours
Pharmacological particulars
Pharmacotherapeutic group: Electrolytes with carbohydrates.
ATCvet code: QB05BB02
Pharmacodynamic properties
The solution is used as a source of water, glucose and electrolytes for animals that cannot be given fluids orally.
Pharmacokinetic properties
Intravenous infusion ensures rapid distribution. The constituents of the infusion solution will be metabolised and excreted through the same pathways as those substances derived from normal dietary sources.
Pharmaceutical particulars
Incompatibilities
Check compatibility of additives prior to administration.
Shelf life
Do not use unless the solution is clear, free from visible particles, and the container is undamaged.
Unopened
100 ml: 18 months.
250 ml, 500 ml, 1000 ml, 2000 ml, 3000 ml and 5000 ml: 2 years.
Special precautions for storage
Do not store above 25°C. Do not freeze.
Immediate packaging
Presented in clear polyvinylchloride (PVC) infusion bags, overwrapped with polypropylene, in cartons of 50 x 100 ml, 20 x 250 ml, 20 x 500 ml, 10 x 1000 ml, 4 x 2000 ml, 4 x 3000 ml and 2 x 5000 ml.
Not all pack sizes may be marketed.
Each carton contains a sufficient number of package leaflets so that individual units may be supplied.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Marketing Authorisation Holder (if different from distributor)
Dechra Limited, Snaygill Industrial Estate, Keighley Road, Skipton, North Yorkshire, BD23 2RW, United Kingdom.
Marketing Authorisation Number
Vm 10434/4058
Significant changes
Date of the first authorisation or date of renewal
9 December 1998
Date of revision of the text
June 2016
Any other information
For animal treatment only. To be supplied only on veterinary prescription. Keep out of the sight and reach of children.
Legal category
Legal category: POM-V
GTIN
GTIN description:Vetivex 18 (Sodium Chloride 0.18% w/v and Glucose 4% w/v Intravenous Infusion BP (Vet)) 500 ml:
GTIN:05055031410835