Target species
Horses
Indications for use, specifying the target species
For the treatment of lameness in horses due to non-infectious inflammation of joints
Contraindications
None known
Special warnings for each target species
This product does not contain an antimicrobial preservative. Any solution remaining in the vial following withdrawal of the required dose should be discarded.
Special precautions for use in animals
See below under "Amounts to be administered and administration route" regarding special precautions in administration.
Special precautions to be taken by the person administering the product to animals
None
Adverse reactions (frequency and seriousness)
In very rare cases, horses may show a transient flare reaction after intra-articular injection. This may present as a diffuse swelling lasting 24 – 48 hours resulting from irritation by the needle while in the joint space. These flares may be acute but will generally resolve without sequelae within a few days
Use during pregnancy, lactation or lay
The product may be used safely in pregnant and lactating animals.
Interaction with other medicinal products and other forms of interaction
None known
Amounts to be administered and administration route
For intravenous or intra-articular use.
The recommended dose is:
Intravenous administration: 4 ml corresponding to 40 mg sodium hyaluronate
Intra-articular administration: 2 ml corresponding to 20 mg sodium hyaluronate
Treatment may be repeated at weekly intervals for a total of three treatments.
Strict aseptic technique should be observed when injecting Hyonate. As with any intra-articular procedure, proper injection site disinfection and animal restraint are very important.
Excess synovial fluid should be aseptically removed prior to injection. Care should be taken not to scratch the cartilage surface with the point of the injection needle. Diffuse swelling lasting 24 to 48 hours may result from irritation by the needle while in the joint space.
For best results, the horse should be given three days stable rest after intra-articular treatment before gradually resuming normal activity.
Withdrawal periods
Meat: zero days.
Milk: Not applicable.