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Date: Saturday, May 18, 2024 16:50

Description: MSD-AH
Telephone: 01908 685685 (Customer Support Centre)
Release 2.72
Nobilis® Erysipelas
 
Species: Turkeys
Therapeutic indication: Immunological veterinary medical products: For turkeys
Active ingredient: Vaccine Antigens
Product:Nobilis® Erysipelas
Product index: Nobilis® Erysipelas
Poultry - meat: Zero days
Incorporating:
Qualitative and quantitative composition
Active substance:
Erysipelothrix rhusiopathiae, strain M2
(serotype 2): ¼ RPU*/ 0.5 ml dose
Adjuvant:
dl α-tocopheryl acetate: 37.5 mg/dose
*1 RPU = 1 Relative Potency Unit, is the calculated potency compared to a reference serum obtained by means of a reference vaccine which has been tested and found to be satisfactory in pigs.
For the full list of excipients, see section "Pharmaceutical particulars".
Pharmaceutical form
Suspension for injection.
Clinical particulars
Target species
Turkeys.
Indications for use
For active immunisation of turkeys to reduce mortality caused by Erysipelothrix rhusiopathiae.
The onset of immunity is 6 weeks post second vaccination and the duration of immunity is 23 weeks post second vaccination.
Contraindications
None.
Special warnings for each target species
Vaccinate healthy animals only.
A good immune response is reliant on the reaction of an immunogenic agent and a fully competent immune system. Immunogenicity of the vaccine antigen will be reduced by poor storage or inappropriate administration. Immuno-competence of the animal may be compromised by a variety of factors including poor health, nutritional status, genetic factors, concurrent drug therapy and stress.
Special precautions for use
None.
Adverse reactions
None.
Use during pregnancy or lactation
Do not vaccinate laying birds or within 2 weeks before onset of the laying period.
Interactions
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis.
Amounts to be administered and administration route
Dose: 0.5 ml
Administration: by subcutaneous injection.
Turkeys are to be vaccinated twice. Subcutaneous injection of 0.5 ml (one dose) of vaccine can take place from six weeks of age onwards. Vaccination is repeated after 4 weeks. The second vaccination for breeder turkeys has to be given not later than two weeks before the onset of the laying period.
Before using the vaccine allow it to reach room temperature (15-25°C) and shake before and intermittently during use. Use sterile syringes and needles. Avoid introduction of contamination by multiple broaching.
Overdose
No particular signs after administration of a double dose.
Withdrawal periods
Zero days.
Pharmacological particulars
ATCvet code: QI01CB02
Pharmacotherapeutic group:
Inactivated bacterial vaccines for Turkeys
The active ingredient is a cell lysate of E. rhusiopathiae strain M2 (serotype 2), which induces protection against turkey erysipelas.
Pharmaceutical particulars
Excipients
dl α-tocopheryl acetate
Polysorbate 80
Simethicone
Sodium chloride
Trometamol (Tris)
Hydrochloric acid
Water for injections.
Major incompatibilities
Do not mix with any other veterinary medicinal product.
Shelf life
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf-life after first opening the immediate packaging: 10 hours.
Special precautions for storage
Store in a refrigerator (between +2 °C and +8 °C). Do not freeze. Protect from light.
Immediate packaging
Bottle of glass, hydrolytical class type I (Ph. Eur.) or PET-flask closed with a halogenobutyl rubber stopper and sealed with a coded aluminium cap.
Package sizes:
1 bottle of 250 ml (500 doses) or 500 ml (1000 doses) packed in a cardboard box.
Not all pack sizes may be marketed.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with the local requirements.
Marketing Authorisation Number
UK: Vm 01708/4546
Significant changes
Date of the first authorisation or date of renewal
26 June 2009.
Date of revision of the text
December 2022.
Any other information
For animal treatment only. Keep out of the sight and reach of children.
Legal category
Legal category: POM-VPS
GTIN
GTIN description:Nobilis Erysipelas 1x500ds/250ml:
GTIN:08713184091673