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Pharmacological particulars
ATC vet code: QI09AB02.
Pharmacotherapeutic group
Inactivated bacterial vaccine.
Vaccine to stimulate active immunity of sows/gilts in order to provide passive immunity to their progeny against E. coli strains that express the fimbrial adhesins F4ab, F4ac, F5 and F6.
The fimbrial adhesins F4ab, F4ac, F5, and F6 are responsible for the adhesion and the virulence of E.coli strains, which cause neonatal enterotoxicosis in piglets. These immunogens are incorporated in an adjuvant in order to enhance a prolonged stimulation of immunity. Neonatal piglets derive passive immunity via ingestion of colostrum from vaccinated sows/gilts.