ATCvet code: QP52AG06
Pharmacotherapeutic group
Anthelmintics, Oxyclozanide
Pharmacodynamic properties
Oxyclozanide is an anthelmintic of the salicylanilide group. It is effective against Fasciola species, acting as an uncoupler of oxidative phosphorylation. It may act at more than one site to decrease levels of ATP leading to metabolic malfunction and death of the parasite.
Pharmacokinetic particulars
Oxyclozanide is slowly absorbed after oral administration with peak plasma levels 24 hours after dosing. Excretion is predominantly faecal, biliary excretion being the most important route of elimination (cattle studies only).