For oral use.
For the prevention of nausea induced by chemotherapy and treatment and prevention of vomiting (except motion sickness), (only for dogs 8 weeks of age or older).
To treat or prevent vomiting, Cerenia tablets should be administered once daily, at a dose of 2 mg maropitant per kg bodyweight, using the number of tablets given in the table below. Tablets are breakable along the score line on the tablet.
To prevent vomiting, tablets should be given more than 1 hour in advance. The duration of the effect is approximately 24 hours and, therefore, tablets can be given the night before administration of an agent that may cause emesis (e.g. chemotherapy).
Cerenia can be used to treat or prevent vomiting either as tablets or as solution for injection administered once daily. Cerenia solution for injection may be administered for up to five days and Cerenia tablets for up to fourteen days.
Prevention of nausea induced by chemotherapy Treatment and prevention of vomiting (except motion sickness) |
Dog bodyweight (kg) | Number of tablets |
16 mg | 24 mg | 60 mg |
3.0 – 4.0* | 1/2 | | |
4.1 – 8.0 | 1 | | |
8.1 – 12.0 | | 1 | |
12.1 – 24.0 | | 2 | |
24.1 – 30.0 | | | 1 |
30.1 – 60.0 | | | 2 |
* Correct dose for dogs of less than 3 kg cannot be accurately achieved.
For prevention of vomiting induced by motion sickness, (only for dogs 16 weeks of age or older)
To prevent vomiting induced by motion sickness, Cerenia tablets should be administered once daily, at a dose of 8 mg maropitant per kg bodyweight, using the numbers of tablets given in the table below. Tablets are breakable along the score line on the tablet.
Tablets should be administered at least one hour before starting the journey. The anti-emetic effect persists for at least 12 hours, which for convenience may allow administration the night before early morning travel. Treatment may be repeated for a maximum of two consecutive days.
As the pharmacokinetic variation is large and maropitant accumulates in the body after once daily repeated administration, lower doses than recommended might be sufficient in some individuals and when repeating the dose.
Prevention of motion sickness |
| Number of tablets |
Dog bodyweight (kg) | 16 mg | 24 mg | 60 mg | 160 mg |
1.0 – 1.5 | | 1/2 | | |
1.6 – 2.0 | 1 | | | |
2.1 – 3.0 | | 1 | | |
3.1 – 4.0 | 2 | | | |
4.1 – 6.0 | | 2 | | |
6.1 – 7.5 | | | 1 | |
7.6 – 10.0 | | | | 1/2 |
10.1 – 15.0 | | | 2 | |
15.1 – 20.0 | | | | 1 |
20.1 – 30.0 | | | | 1 1/2 |
30.1 – 40.0 | | | | 2 |
40.1 – 60.0 | | | | 3 |
For motion sickness, a light meal or snack before dosing is recommended; prolonged fasting before administration should be avoided. However, Cerenia tablets should not be administered wrapped or encapsulated in food as this may delay dissolution of the tablet and consequently the onset of efficacy.
Dogs should be carefully observed following administration to ensure that each tablet is swallowed.