For external use on cattle only.
Not to be used in other species as severe adverse reactions, including fatalities in dogs, may occur.
To avoid possible secondary reactions due to the death of Hypoderma larvae in the spine or oesophagus, it is recommended to administer CYDECTIN Pour-On at the end of the period of warble fly activity, and before the larvae reach their resting sites. Consult your veterinary surgeon on the correct timing of treatment.
Reactions at the site of application may occur after application in very rare occasions. Neurological signs (including ataxia, trembling and lethargy have been reported in very rare cases (less than 1 animal in 10,000 animals treated, including isolated reports).
Withdrawal period
Meat and offal: 14 days.
Milk: 6 days (144 hours).
Operator warnings
Do not eat, drink or smoke whilst handling the product.
Wear protective clothes and gloves when applying the product.
Wash hands after use.
Avoid direct contact with human skin and eyes.
If splashed in the eye or on the skin, wash with plenty of clean, running water immediately.
Other precautions regarding impact on the environment
Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT) substance; therefore, exposure of the environment to moxidectin must be limited to the extent possible. Treatments should be administered only when necessary and should be based on faecal egg counts or evaluation of the risk of infestation at the animal and/or herd level.
Like other macrocyclic lactones, moxidectin has the potential to adversely affect non-target organisms:
•Faeces containing moxidectin excreted onto pasture by treated animals may temporarily reduce the abundance of dung feeding organisms. Following treatment of cattle with the product, levels of moxidectin that are potentially toxic to dung fly species may be excreted over a period more than 2 weeks and may decrease dung fly abundance during that period. It has been established in laboratory tests that moxidectin may temporarily affect dung beetle reproduction; however, field studies indicate no-long term effects. Nevertheless, in case of repeated treatments with moxidectin (as with products of the same anthelmintic class) it is advisable not to treat animals every time on the same pasture to allow dung fauna populations to recover.
•Moxidectin is inherently toxic to aquatic organisms including fish. The product should be used only according to the label instructions. Based on the excretion profile of moxidectin when administered as the pour-on formulation, treated animals should not have access to watercourses during the first week after treatment.