FOR ANIMAL TREATMENT ONLY
Do not vaccinate sick birds.
Do not use in infected flocks showing clinical signs.
Do not use in laying or breeding hens.
Adverse Reactions
The administration of a single dose to 10-day old chickens causes lymphocyte depletion in the bursa of Fabricius (in 75-100% of the follicles). Lymphocyte repopulation is observed from 21 days post vaccination onwards. At 28 days post vaccination there is still depletion remaining (25-75% of follicles). As a consequence vaccination with Poulvac Bursa Plus may induce immunosuppression. If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.
Special warnings
Use only in flocks with maternal antibody levels of ≤500 ELISA units.
The optimum age for vaccination may be determined with the following method:
Determine the ELISA* antibody titres against Gumboro Disease in 20 chickens of 1 day of age.
For each result, calculate the square root.
Calculate the average square root for all data (M).
The age for vaccination (J) is calculated with the formula:
* Method valid for data collected with the Idexx FlockCheck®: Anti-IBD assay kit.
Whatever the vaccination day calculation reaches, do not vaccinate birds less than 10 days of age.
Use carefully as Poulvac Bursa Plus spreads from bird to bird and may also spread to nearby flocks. Reversion to virulence studies conducted at the laboratory level demonstrated that there is no increase in virulence after 5 passages in chickens. However, it is recommended to avoid spreading, especially to laying birds.
Due to its residual pathogenicity to the bursae the vaccine should be used only in case of outbreaks of very virulent IBDV strains.
Vaccine strain V877 induces a lesion score of around 2.7 to the bursa of Fabricius observed 28 days after administration of 50 maximum doses to 10-day old chickens.
Interaction with vaccination against Newcastle Disease has been studied. No significant interference in protection against Newcastle Disease virus virulent challenge is observed in birds vaccinated at 10 days of age with Poulvac Bursa Plus and 7 days later with a live Newcastle disease vaccine. However, a statistically lower serological response to Newcastle Disease virus was observed in birds vaccinated with Poulvac Bursa Plus. As a consequence a transient immunodepression following vaccination with Poulvac Bursa Plus cannot be excluded.
Do not mix with any other veterinary medicinal product.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Operator warnings
Wash and disinfect hands and equipment after vaccination.
Withdrawal period
Zero days.