A lyophilised vaccine containing live avian infectious bronchitis virus Massachusetts 1263 strain and Arkansas 3168 strain at 103.3 - 105.8 EID50* per dose.

*EID50: Embryo infective dose 50%

For the active immunisation of broilers to reduce the severity of upper respiratory tract infections caused by Massachusetts and 793/B/91-type strains of avian infectious bronchitis virus.

Onset of immunity: 21 days after vaccination.

Duration of immunity: 6 weeks after vaccination.

Coarse spray vaccination from one day of age.

This vaccine has been used in most types of spray equipment, hand-sprayers (e.g. ASL Polyspray 2), knapsack sprayers (e.g. Birchmeyer with 0.55 or 1.6 mm spray nozzle, Gloria with 1.0 mm nozzle) or automatic spraying equipment (e.g. Bimex). The apparatus should be set to deliver a coarse spray (droplet size of 80-160 micrometres), allowing a dose of 0.5 ml per bird.

The lyophilised vaccine should be reconstituted with water of good quality at room temperature e.g. deionised water or good quality drinking water.

The lyophilised vaccine should be reconstituted as follows:

Remove the aluminium cap from the vial. To reconstitute the lyophilised vaccine, the rubber stopper should be removed whilst the vial is immersed in a plastic measuring jug containing 0.5 litre of clean cool water.

Half fill the vial with water, replace the stopper and shake to remove any remnants in the vial.

The content of the vial should then be added to the water in the jug, mixed well and transferred to the sprayer tank and thoroughly mixed.

For the 5,000 dose vial a total amount of 2.5 L water is required and for the 10,000 dose vial a total amount of 5 L water should be used.

The chickens should be sprayed in chick boxes or brooding rings in the house to avoid loss of vaccine virus.

Vaccinate healthy animals only. Do not re-vaccinate birds.

Spray vaccination should not be used if an intercurrent infection is suspected.

Avian infectious bronchitis virus strains Massachusetts and Arkansas may spread to in contact birds. The duration of spreading of the vaccine virus is for up to 30 days following vaccination. It is recommended that all chickens on a site be vaccinated with this product. Do not use on mixed sites of broilers and breeders.

The product should only be used where it has been established that 793/B/91 like avian infectious bronchitis virus serotypes are epidemiologically relevant in the area.

Special precautions should be taken to avoid spread of the vaccine virus from vaccinates to pheasants.

Do not use in birds intended for laying or breeding.

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis.

Do not mix with any other medicinal product.

Commonly a slight transient respiratory reaction, including gasping, snicking and raling, may be observed for approximately three days.

The frequency of adverse reactions is defined using the following convention:

Administration of a 10-fold overdose does not result in symptoms different from those mentioned above.

Personal protective equipment consisting of goggles and dust mask or a helmet with filtered air circulation should worn when handling the veterinary medicinal product.

Zero days.

Store and transport refrigerated (2°C - 8°C).

Protect from light. Do not freeze.

Shelf life after reconstitution according to directions: 2 hours.

Keep out of the sight and reach of children.

For animal treatment only

10ml glass vial containing 5,000 doses (Pack of 10 vials)

20ml glass vial containing 10,000 doses (Pack of 10 vials)

Not all pack sizes may be marketed.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.