Do not use in sick chickens.
Do not use in birds in lay.
Adverse reactions
No local or systemic reactions have been observed following the administration of the vaccine during safety studies. However, and in common with other immunological products, it is expected that local or systemic reactions may occur in a very small proportion of vaccinated birds.
No local or systemic reactions have been observed after the administration of a tenfold overdose.
Safety and efficacy data are available which demonstrate that this vaccine can be mixed and administered with Poulvac Marek Diluent or Poulvac MD Vac. Do not mix with any other veterinary medicinal product.
Safety and efficacy data are available which demonstrate that this vaccine can be administered on the same day but not mixed with Poulvac IB H120, Poulvac NDW, Poulvac TRT and Poulvac MD Vac. In the case of products administered parenterally, the products should be given at different sites.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except the products mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Special warnings
Vaccine virus spreads from bird to bird. In a study in highly susceptible Rhode Island Red Birds, vaccine virus was shown to increase in virulence after ten passages.
Maternally derived antibody (MDA) can interfere with the development of active immunity. Where it is likely that recent field infection or vaccination of the parent flock has stimulated a high antibody titre and consequently a high level of MDA, the timing of the vaccination programme should be planned accordingly.
Special precautions for use in animals
Avoid stress in chickens before and after vaccination.
Avoid injection into or near joints and tendons.
Operator Warnings
To avoid all possible risks of working with liquid nitrogen and/or explosion of glass ampoules, the following precautions must be taken.
- Use of gloves
- Use of facial protection or safety goggles.
- Use of skin- covering clothing.
Liquid nitrogen causes serious freeze burns and thawing ampoules may occasionally explode after removal from the liquid nitrogen. Operators must protect their face with a visor or goggles and hands with gloves, when handling liquid nitrogen containers and when thawing ampoules.
If liquid nitrogen is spilt and comes into contact with skin causing frost bite injuries immediately:
Warm affected area by immersion in water at 29 ± 1°C or by the use of body heat. Considerable pain will be experienced during warming but this is normal. Do not rub the affected area. Seek medical advice if full function and feeling are not rapidly restored.
After handling vaccine, operators should wash and disinfect their hands with an approved disinfectant.
Withdrawal period
Zero days.