Do not use in animals suffering from cardiac, hepatic or renal impairment.
Do not use in animals suffering from gastro-intestinal ulceration or bleeding.
Do not use where there is evidence of a blood dyscrasia.
Do not use in cases of known hypersensitivity to the active substance or to any of the excipients.
Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of increased renal toxicity. Concurrent administration of potentially nephrotoxic drugs should be avoided.
Do not exceed the stated dose or the duration of treatment.
Do not administer other NSAIDs concurrently or within 24 hours of each other.
As NSAID therapy can be accompanied by gastro-intestinal or renal impairment, adjunctive fluid therapy should be considered especially in the case of acute mastitis treatment.
No significant drug interactions have been reported for carprofen. During clinical studies in cattle four different antibiotic classes were used, macrolides, tetracyclines, cephalosporins and potentiated penicillins without known interactions.
In common with other NSAIDs, carprofen should not be administered simultaneously with another veterinary medicinal product of the NSAID or glucocorticoid class.
NSAIDs are highly bound to plasma proteins and may compete with other highly bound drugs, such that concomitant administration may result in toxic effects. However, during clinical studies in cattle four different antibiotic classes were used; macrolides, tetracyclines, cephalosporins and potentiated penicillins without known interactions.
Studies in cattle have shown that a transient local reaction may form at the site of the injection.
Withdrawal period
Cattle (meat): 21 days.
Cattle (milk): Zero days.
User warnings
Carprofen, in common with other NSAIDs, has been shown to exhibit photosensitizing potential in laboratory studies. Avoid skin contact with Rimadyl Cattle. Should this occur, wash the affected areas immediately.