Reconstitute the vaccine by adding the liquid fraction to the freeze dried vial containing the lyophilised plug.
When the lyophilised plug and liquid fraction are in equally sized vials:
•Inject the entire liquid fraction into the freeze dried vial.
When the lyophilised plug is in a smaller sized vial than the liquid fraction, the reconstitution of the vaccine is carried out in 2 steps:
•Inject 10ml of the liquid fraction on the lyophilised plug in the freeze dried vial.
•Shake well and extract the part reconstituted vaccine from the freeze dried vial and mix with the remaining liquid in the liquid fraction vial.
Shake well before use.
Vaccination programme
For cattle over 3 months of age
Two doses of 5ml of reconstituted vaccine should be given three to four weeks apart to cattle over the age of 3 months, via the intramuscular route.
Ideally, calves should be vaccinated at least 2 weeks before transport, mixing of animals of different origins, housing or any other event which may cause the animals to be stressed or exposed to new infections. Calves are usually most susceptible during early autumn. The vaccine will protect animals against BRSV, PI3, IBR and BVD for at least 6 months, which will cover the period of risk from respiratory infections.
Should cattle be at risk from these respiratory diseases at a subsequent time, the same vaccination scheme is recommended at least 14 days prior to the period of expected disease challenge.
For cattle over 3 weeks of age
For cattle from 3 weeks of age, vaccination leads to seroconversion of seronegative calves vaccinated at 3 and 6 weeks of age. The influence of maternally derived antibodies has not been studied in detail and it is therefore recommended that calves vaccinated before 12 weeks of age are re-vaccinated at 12 weeks of age.