Before using any combinations consult the contra-indications and warnings that appear on the other products' data sheets.
HORSE
Withdrawal Period:
Meat & Offal: Zero days.
Torbugesic
Do not use in horses with a history of liver disease. The most commonly observed side-effect is slight ataxia which may persist for 3–10 minutes. Mild sedation may occur in approximately 15% of horses.
Torbugesic/detomidine hydrochloride combination
Do not use in horses with a history of liver disease. The combination should not be used in pregnant animals nor in animals suffering from colic. Routine cardiac auscultation should be performed prior to use of this combination.
Do not use the combination in horses with a pre-existing cardiac dysrhythmia or bradycardia. Mild to severe ataxia may be encountered but clinical studies have shown that horses are unlikely to collapse. Normal precautions should be observed to prevent patient self-injury.
Torbugesic/romifidine combination
Do not use in horses with a history of liver disease. The combination should not be used during the last month of pregnancy.
DOG
If respiratory depression occurs, naloxone may be used as an antidote. Do not use in dogs with a history of liver disease. Transient ataxia, anorexia and diarrhoea have been reported as occurring rarely. When using Torbugesic as a pre-anaesthetic the use of an anti-cholinergic, such as atropine will protect the heart against possible narcotic-induced bradycardia. When administering as an intravenous injection do not inject as a bolus.
CAT
If respiratory depression occurs, naloxone may be used as an antidote. Do not use in cats with a history of liver disease. Cats should be weighed to ensure that the correct dose is calculated. Use of either insulin syringes or 1 ml graduated syringes is recommended to ensure accurate dosing. Marked sedation does not occur in cats when Torbugesic Injection is used as a sole agent. Mydriasis is likely to occur.
Operator warning
Butorphanol has opioid-like activity. Precautions should be taken to avoid accidental injection/self-injection with this potent drug. If accidental self-injection occurs, seek immediate medical attention showing a copy of product literature. Do not drive. The effects of butorphanol include sedation, dizziness and confusion. Effects can be reversed with an opioid antagonist. Wash splashes from skin and eyes immediately.