1Not to be used in horses intended for human consumption.
2Do not administer by the intra-carotid route.
3Virbaxyl 10% should not be administered in the last month of pregnancy because of the risk of inducing premature parturition.
4As the safety of xylazine during organogenesis has not been fully demonstrated by current methods it should be used with caution during the 1st month of pregnancy.
5Careful consideration should be given before administering to animals exposed to stress conditions such as extreme heat, cold, high altitude or fatigue.
6Side effects such as brachycardia, cardiac arrhytmia and polyuria may occur.
7Following intravenous administration, a transient rise followed by a fall in blood pressure usually occur.
Operator warnings
8Xylazine is an alpha adrenoceptor agonist acting primarily on alpha-2 receptors.
9Precautions should be taken to avoid accidental injection/self-injection.
10Wash splashes from the skin immediately.
11In the event of accidental injection/self-injection, seek urgent medical advice and show label and other product literature. DO NOT DRIVE as sedation and changes in blood pressure may occur.
12Remove contaminated clothes that are in direct contact with the skin
13In the case of accidental contact of the product with the eyes, rinse with large amounts of fresh water. If symptoms occur, seek the advice of a doctor
14If pregnant women handle the product, special precaution should be observed not to self-inject as uterine contractions and decreased foetal blood pressure may occur after accidental systemic exposure
Advice to doctors
Xylazine is an alpha adrenoceptor agonist whose toxicity may cause clinical effects including sedation, respiratory depression, and coma, bradycardia hypotension and hyperglycaemia. Ventricular arrhythmias have also been reported. Treatment should be supportive with appropriate intensive therapy.