Chickens (breeding birds).

For the active immunisation of parent birds for the passive immunisation of their progeny, to reduce mortality and clinical signs of disease caused by avian reoviruses.

Active immunity develops in the parent within 4 weeks, and offspring born at any stage of the subsequent laying period will have passive immunity against reovirus infections for protection during the susceptible period in the early phase of life.

None.

Vaccinate healthy birds only.

None.

This veterinary medicinal product contains mineral oil. Accidental injection/self injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given.

If you are accidentally injected with this product, seek prompt medical advice even if only a very small amount is injected and take the package leaflet with you.

If pain persists for more than 12 hours after medical examination, seek medical advice again.

This veterinary medicinal product contains mineral oil. Even if small amounts have been injected, accidental injection with this product can cause intense swelling, which may, for example, result in ischaemic necrosis and even the loss of a digit. Expert, PROMPT, surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon.

It is very common that a slight transient swelling (resolved within 3 weeks) may be felt in 50% of the vaccinated birds at the site of vaccination.

The frequency of adverse reactions is defined using the following convention:

- very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)

- common (more than 1 but less than 10 animals in 100 animals)

- uncommon (more than 1 but less than 10 animals in 1,000 animals)

- rare (more than 1 but less than 10 animals in 10,000 animals)

- very rare (less than 1 animal in 10,000 animals, including isolated reports).

Do not use in birds in lay and within 4 weeks before the onset of the laying period.

Safety and/or efficacy data are available which demonstrate that this vaccine can be administered the same day but not mixed with other Intervet inactivated oil emulsion vaccines, containing the avian infectious bronchitis (IB), Gumboro disease (GD), Newcastle disease (ND), turkey rhinotracheitis (TRT) and/or egg drop syndrome (EDS) antigens.

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product apart from the products listed above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case-by-case basis.

Intramuscular or subcutaneous use.

The vaccine Nobilis Reo inac should be given to birds around 10-20 weeks of age but not later than 4 weeks before the expected onset of lay.

Dose: 0.5 ml vaccine per bird via intramuscular injection in the thigh or chest muscle or by subcutaneous injection into the back of the neck, using a medium sized needle (20g x ½”). For an optimal response in birds not primed by field virus, two vaccinations should be given approximately 6 weeks apart.

Allow the vaccine to reach ambient temperature (15 ºC - 25 ºC) before use.

The vaccine may occasionally separate into two layers on storage. This in no way affects its potency, but the vaccine should be shaken vigorously before and during use to ensure a good emulsification.

An automatic injection system, incorporating a means to prevent back flushing and hence possible contamination of the vaccine, should be used to administer the vaccine.

Ensure that vaccination equipment is clean and sterile before use. Do not use vaccination equipment with rubber parts as the excipient may damage certain types of rubber.

Not different from single dose.

Zero days.