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Dosage and administration
Oral use.
Pre-ruminant cattle: administration in milk/milk replacer.
Pigs: administration in drinking water.
Duration of treatment: 3-5 days.
Pre-ruminant cattle: 25-50 mg paromomycin sulfate per kg BW/day (equivalent to 0.125 – 0.25 ml of product/kg BW/day).
Pigs: 25-40 mg paromomycin sulfate per kg BW/day (equivalent to 0.125 – 0.2 ml of product/kg BW/day).
To ensure accurate measurement of the required volume of product, suitably calibrated measuring equipment should be used.
For administration via drinking water, milk or milk replacer, the exact daily amount of product should be calculated, based on the recommended dose, and the number and weight of the animals to be treated, according to the following formula:
ml product / kg body weight / day
x
Mean body weight (kg) of animals to be treated
= .... ml product per liter drinking water /milk/milk replacer
Mean daily water/milk/milk replacer consumption (litre) per animal
To ensure a correct dosage body weight should be determined as accurately as possible.
The uptake of medicated water/milk /milk replacer depends on several factors including clinical conditions of the animals and the local conditions such as ambient temperature and humidity. In order to obtain the correct dosage, drinking water/milk/milk replacer uptake has to be monitored and the concentration of paromomycin has to be adjusted accordingly.
Medicated drinking water/milk/milk replacer and any stock solutions should be freshly prepared by carefully mixing the product in the requisite quantity of fresh potable water /milk/milk replacer every 6 hours (in milk/milk replacer) or every 24 hours (in water).
Withdrawal Period:
Pre-ruminant cattle: meat and offal - 20 days
Pigs: meat and offal - 3 days