Target species
Pigs
Indications for use, specifying the target species
Flubendazole is a broad spectrum anthelmintic for oral administration, active against mature and immature stages of the following nematodes of the gastro-intestinal tract of the pig:
Ascaris suum (large roundworm)
Hyostrongylus rubidus (red stomach worm)
Oesophagostomum dentatum (nodular worm)
Trichuris suis (whip worm)
Strongyloides ransomi (threadworm) (adult).
Metastrongylus apri (lungworm).
Flubendazole is ovicidal.
Contra-indications
Not applicable.
Special warnings for target species
None.
Special precautions for use
None.
Special precautions for use in animals
None.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Accidental ingestion by humans should be avoided. May cause sensitisation by skin contact. May cause skin and eye irritation. Avoid direct skin contact. Wear overalls, safety glasses and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water. If the operations involve potential exposure to dust, wear either a disposable filter and half-mask respirator conforming to European Standard EN149, or a non-disposable respirator to European Standard EN140 fitted with a filter to EN143.
Adverse reactions (frequency and seriousness)
None known.
Use during pregnancy, lactation or lay
Not applicable.
Interaction with other medicinal products and other forms of interaction
None known.
Amounts to be administered and administration route
For oral administration only.
For incorporation into dry feed at a registered mill.
A manufacturer who is approved to incorporate directly at any concentration, veterinary medicinal products or premixtures containing such products, must be responsible for mixing when incorporation is less than 2 kg per tonne for final feed.
Dosage
The standard recommended total dosage is 5 mg flubendazole per kg bodyweight.
The amount of product to be incorporated should be calculated according to the average bodyweight of the pigs to be treated.
Incorporation and dosing instructions
If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or over-dosing.
As a guide, the following incorporation rates are suggested:
Standard dosing regime
Incorporation:
Add 600 g of Flubenol 5 %w/w Premix to at least 5 kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can then be fed as mash or pellets. This gives 30 mg flubendazole per kg of finished feed.
Breeding stock should be treated for 10 consecutive days. Weaners and fattening pigs –should be treated for 5 consecutive days, or the event of a heavy Trichuris infestation, for 10 consecutive days.
Variable dosing regime
To facilitate feeding for different lengths of time to suit the intervals between feed deliveries, the standard dosage can be divided and administered over differing periods of time, as shown below.
Incorporation:
Add the required amount of Flubenol 5% Premix to at least 5kg of one of the feed ingredients. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can then be fed as mash or pellets.
a) Breeding stock
Amount of Flubenol 5 % w/w to add to each 5 kg premix for making up each tonne of final feed | Flubendazole inclusion rate in final feed (mg/kg) | Duration of treatment (days) | Total dose of flubendazole (mg/kg bodyweight) | Uses |
400 g | 20 | 14 | 5 | Ascaris suum, Oesophagostomum dentatum and Hyostrongylus rubidus |
300 g | 15 | 21 | 5 |
200 g | 10 | 28 | 5 |
b) Weaners and fattening pigs
Amount of Flubenol 5 % w/w to add to each 5 kg premix for making up each tonne of final feed | Flubendazole inclusion rate in final feed (mg/kg) | Duration of treatment (days) | Total dose of flubendazole (mg/kg bodyweight) | Uses |
200 g | 10 | 14 | 5 | Ascaris suum, Oesophagostomum dentatum and Hyostrongylus rubidus |
150 g | 7.5 | 21 | 5 |
In the event of a heavy Trichuris infestation, use 600 g/tonne (30 mg/kg final feed) for 10 days.
Treatment frequency:
Pigs should be treated twice a year unless recommended otherwise by a veterinary surgeon. Pigs brought onto the premises should be treated on arrival and before mixing with other animals.
Treatment of clinical worm infestations:
Treat relevant infestations at the following intervals:
Lungworm: every 3 - 4 weeks
Nodular worm: every 2 months
Large round worm: every 2 months
Red stomach worm: every month
Whipworm: every 6 weeks
Consult a veterinary surgeon for initial identification of problem species.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Flubendazole is an analog of mebendazole for which the side effects of overdose include transient gastrointestinal abnormalities.
Withdrawal period(s)
Animals must not be slaughtered for human consumption during treatment.
Pigs may be slaughtered for human consumption only after 7 days from the last treatment.