Target species
Sheep and lambs
Indications for use, specifying the target species
For the control of chronic and subacute fascioliasis (due to Fasciola hepatica) in sheep and lambs.
For the control of Oestrus ovis (Sheep Nasal Bot Fly).
For the control of inhibited, immature and adult stages of Haemonchus contortus (Barber Pole Worm) including benzimidazole resistant strains.
Flukiver is active against mature and immature flukes.
Fluke activity:
Stage | Percentage kill |
Adults | 97-100 % |
6-8 weeks immature | 91-95% |
5 weeks immature | 91% |
3-4 weeks immature | 23-73 % |
Ticks (Ixodes ricinus) feeding on sheep at the time of treatment are likely to produce fewer viable eggs.
Contraindications
None
Special warnings for target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
∙ Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
∙ Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to closantel has been reported in Haemonchus in outside the EU. The use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Special precautions for use
i. Special precautions for use in animals
When using a drenching gun, take care not to injure the mouth or pharynx.
Do not exceed the stated dose.
ii. Special precautions to be taken by the person administering the veterinary medicinal product to animals
Wash hands after administration.
Adverse reactions (frequency and seriousness)
None known. Flukiver can be used in all age groups of sheep and lambs. It can also be used in rams at any time including during the breeding season.
Use during pregnancy, lactation or lay
Flukiver can be used at any time during pregnancy.
Interaction with other medicinal products and other forms of interaction
No interactions have been observed.
Amounts to be administered and administration route
1 ml of Flukiver per 5 kg bodyweight (ie 10 mg closantel per kg bodyweight).
For example:
Bodyweight | Dose |
Up to 5 kg | 1 ml |
10 kg | 2 ml |
20 kg | 4 ml |
30 kg | 6 ml |
40 kg | 8 ml |
50 kg | 10 ml |
60 kg | 12 ml |
70 kg | 14 ml |
80 kg | 16 ml |
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.
Give orally as a drench. Suitable for use with most types of standard drenching equipment.
Shake well before use.
Do not mix with other products.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Symptoms of acute overdosage are decreased vision or blindness, anorexia, in-coordination and general weakness.
Withdrawal period(s)
Meat: 42 days
Not authorised for use in ewes producing milk for human consumption including during the dry period. Do not use within 1 year prior to the first lambing in ewes intended to produce milk for human consumption.