PG 600 is a freeze dried presentation of hCG and PMSG in combination with solvent for reconstitution. PG 600 contains 400iu of PMSG and 200iu of hCG. PMSG and hCG are two large glycoproteins composed of two non-covalently associated alpha and beta subunits. The extensive glycosylation of the CTP tail of the beta subunits of PMSG and hCG results in the extended half life typical of both hormones which reaches, in pigs, 27 and 36 hours for hCG and PMSG respectively. PMSG displays dual FSH and LH activities. It therefore stimulates follicular growth and follicular maturation during the days preceding oestrus and ovulation. HCG displays only LH like activity. It therefore plays a key role in the induction of ovulation of the follicles stimulated to grow by PMSG. This explains why PG600 efficiently induces and synchronizes puberty (gilts) and the first post weaning ovulation (sows).

After injection to pigs, PMSG and hCG are rapidly absorbed as, for both hormones, Cmax is reached within 8 hours for both hormones. Bioavailability following i.m. injection is high. In pigs, the elimination half lives of PMSG and hCG were shown to be 36 and 27 hours respectively.