Do not use in very cold conditions as cardiovascular collapse and hypothermia (increased by inhibition of hypothalamic heat regulation centre) due to peripheral vasodilation may occur.
The veterinary medicinal product is contraindicated for use in transport or for re-grouping of pigs which will be slaughtered prior to the end of the withdrawal period.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Special warnings for each target species
During onset of action treated animals should be left alone in a quiet environment. Injection into adipose tissue may lead to apparent insufficient effect.
Occasional deaths have been observed in Vietnamese Pot Bellied pigs. It is thought this may be caused by injection into the fat leading to slow induction and tendency to use additional doses, leading to overdosage. It is important with this breed not to exceed the stated dose.
Do not re-inject if the animal is unresponsive to the initial dose, allow full recovery before re-injecting on a different day.
Special precautions for use
Special precautions for use in animals Not Applicable
Special precautions to be taken by the person administering the veterinary medicinal product to animals Azaperone, sodium metabisulfite, and methyl and propyl parahydroxybenzoate can cause hypersensitivity reactions. People with known hypersensitivity to Azaperone or any of the excipients should avoid contact with the product.
This product may be irritant to the skin, eyes and oral mucosa. Avoid contact with the skin, eyes and oral mucosa. Wash any splashes from skin, eyes and oral mucosa immediately with plenty of water. Seek medical advice if irritation persists.
Accidental self-injection or ingestion may result in sedation. Care should be taken to avoid accidental self-injection. Only carry this veterinary medicinal product in an unarmed syringe to avoid accidental injection. In case of accidental self-injection seek medical advice immediately and show the package leaflet or the label to the physician. DO NOT DRIVE.
The veterinary medicinal product should not be administered by pregnant women. No data is available on the presence of azaperone in the milk of breastfeeding women. Breastfeeding women should handle the veterinary medicinal product with extreme caution.
Wash hands after use.
Adverse reactions (frequency and seriousness)
Salivation, tremor and panting may occur at the highest dose recommended. These side effects disappear spontaneously and leave no lasting damage.
Reversible penis prolapse may occur in boars.
Use during pregnancy, lactation or lay
Can be used during pregnancy and lactation.
Interaction with other medicinal products and other forms of interaction
− Azaperone has a potentiating effect on all centrally suppressive substances and hypotensive substances (due to peripheral α-adrenolysis).
− Amplification of tachycardia caused by adrenolytic agents.
− Simultaneous use with α- and β-sympathomimetic substances such as epinephrine (adrenaline) results in hypotension (“adrenaline reversal”).
Withdrawal period
Meat and offal: 18 days.