ATCvet code: QI05AB01 – streptococcus.

The vaccine contains recombinant protein antigens derived from Streptococcus equi, which are not living and cannot spread to other animals. Strangvac stimulates active immunity against Streptococcus equi, the causative agent of strangles in horses. After vaccination, in addition to antibodies in the blood, local antibodies (IgG) can also be detected in secretions from the nasal passages. The immunogenicity of the Streptococcus equi antigens is enhanced by ISCOM (Immune Stimulating COMplex). Based on measured antibody titers immunological memory response was found in horses following repeated vaccination 6 months after primary vaccination. The role of the measured antibodies in the immune response relevant for the protection against strangles is not known.

Strangvac does not contain the DNA targets of diagnostic qPCR tests for Streptococcus equi or the A and C antigens used in the iELISA diagnostic test for exposure to Streptococcus equi.