People with known hypersensitivity to benzyl alcohol should avoid contact with the product.
Do not eat, drink or smoke while handling the product.
Do not use in pregnant animals, for which induction of abortion or parturition is not intended. Do not use in animals with spastic diseases of the respiratory or gastrointestinal tract.
Adverse Reactions
Anaerobic infection may occur if anaerobic bacteria penetrate the tissue at injection site, in particular following intramuscular injection.
When used for induction of parturition and dependent on the time of treatment relative to the date of conception, the incidence of retained placenta may be increased.
In very rare cases, anaphylactic-type reactions can be observed which might be life-threatening and require rapid medical care.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated, displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated )
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Interaction with other medicines
Concurrent use of oxytocin and cloprostenol increases effects on the uterus. The activity of other oxytocic agents can be increased after the administration of cloprostenol.
Do not use in animals being treated with non-steroidal anti-inflammatories, as the synthesis of endogenous prostaglandins is inhibited.
Overdose
Therapeutic tolerance in cattle is broad. Overdoses of more than 10 times are generally well tolerated. Large overdoses may cause transient diarrhoea. No antidotes are available.
An overdose will not accelerate corpus luteum regression.
Withdrawal periods
Meat and offal: 2 days
Milk: Zero days