No sign of toxicity appeared up to 1.5 mg/kg (3 times the recommended dose rate). No antidote has been identified. Do not use in cases of known hypersensitivity to the active ingredient. Do not apply to areas of skin which have mange scabs or other lesions or to areas contaminated with mud or manure.

Frequent and repeated use may lead to the development of resistance. To avoid secondary reactions due to the death of Hypoderma larvae in the oesophagus or in the spine, it is recommended to administer the product at the end of the period of warble fly activity and before the larvae reach their resting site. Do not treat cattle when hair or hide is wet. Do not treat cattle if rain is expected, as rain within 2 hours of treatment may reduce efficacy. However, the efficacy of the product against established infections of O. ostertagi or D. viviparus is not adversely affected if the hide is wet or if rain falls shortly after treatment.

The influence of extreme climatic conditions on persistent activity of the product is unknown.

The product has been formulated for topical application specifically for cattle. It should not be administered to other species as severe adverse reactions, including fatalities in dogs, may occur.

Withdrawal periods: Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 28 days from the last treatment. Do not use in cows producing milk for human consumption, in non-lactating dairy cows including pregnant heifers within 60 days of calving.

EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with the product or used container.