Introduction

Alstoe

Company name: Alstoe Ltd

Address: Sheriff Hutton Industrial Park

Sheriff Hutton

York

YO60 6RZ

Telephone: 01347 878606

Fax: 01347 878333

Email: info@alstoe.co.uk

Website: www.alstoe.co.uk

Presentation

A clear pour-on solution containing ivermectin 0.5% w/v (5 mg/mL).

Uses

Alstomec Pour-on Solution 0.5% at the recommended dose rate of 500 micrograms ivermectin per kg bodyweight is used for the treatment of the following species of gastrointestinal roundworms, lungworms, warbles, mites and lice in cattle. Gastrointestinal roundworms (adults and fourth stage larvae): Ostertagia ostertagi (including inhibited O ostertagi), Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia spp, Oesophagostomum radiatum, Strongyloides papillosus (adult), Trichuris spp (adult). Lungworms (adult and fourth stage larvae): Dictyocaulus viviparus. Eye worms (adult): Thelazia spp. Warbles (parasitic stages): Hypoderma bovis, Hypoderma lineatum. Mites: Chorioptes bovis (reduction of infestation), Sarcoptes scabiei var bovis. Sucking lice: Linognathus vituli, Haematopinus eurysternus. Biting Lice: Damalinia bovis.

The product given at the recommended dose rate of 500 micrograms/kg bodyweight has persistent activity against Trichostrongylus axei and Cooperia spp. acquired during the 14 days after treatment, only if the whole herd is treated simultaneously; Ostertagia ostertagi and Oesophagostomum radiatum acquired during the first 21 days after treatment; Dictyocaulus viviparus acquired during the first 28 days after treatment. It also has a persistent activity against horn flies (Haematobia irritans) for 28 days after treatment, partial efficacy may last for up to 35 days post application. Occasionally variable activity may be observed against Haemonchus placei (L4), Cooperia spp, Trichostrongylus axei and Trichostrongylus colubriformis.

Dosage and administration

For single topical administration 1 mL per 10 kg bodyweight (based on a recommended dosage level of 500 micrograms/kg bodyweight).

The formulation should be applied along the mid-line of the back in a narrow strip between the withers and tailhead. The product should be used with appropriate dosing equipment. The interval between 2 treatments should be at least 28 days.

Contra-indications, warnings, etc

No sign of toxicity appeared up to 1.5 mg/kg (3 times the recommended dose rate). No antidote has been identified. Do not use in cases of known hypersensitivity to the active ingredient. Do not apply to areas of skin which have mange scabs or other lesions or to areas contaminated with mud or manure.

Frequent and repeated use may lead to the development of resistance. To avoid secondary reactions due to the death of Hypoderma larvae in the oesophagus or in the spine, it is recommended to administer the product at the end of the period of warble fly activity and before the larvae reach their resting site. Do not treat cattle when hair or hide is wet. Do not treat cattle if rain is expected, as rain within 2 hours of treatment may reduce efficacy. However, the efficacy of the product against established infections of O. ostertagi or D. viviparus is not adversely affected if the hide is wet or if rain falls shortly after treatment.

The influence of extreme climatic conditions on persistent activity of the product is unknown.

The product has been formulated for topical application specifically for cattle. It should not be administered to other species as severe adverse reactions, including fatalities in dogs, may occur.

Withdrawal periods: Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 28 days from the last treatment. Do not use in cows producing milk for human consumption, in non-lactating dairy cows including pregnant heifers within 60 days of calving.

EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with the product or used container.

Pharmaceutical precautions

Highly flammable - keep away from heat, sparks, open flame or other sources of ignition. Close container when not in use. Bottles should remain upright during storage. Protect from light.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Keep out of the reach of children.

Legal category

POM-VPS

Packaging Quantities

Carton containing 2.5 L plastic bottle.

Further information

The product can be administered to beef cows at any stage of pregnancy or lactation provided that the milk is not intended for human consumption. Not permitted for use in lactating animals producing milk for human consumption. The product will not affect the fertility of cows and bulls and can be given to all ages of animals including young calves.

Precautions to be taken by the person administering the product to animals: the product may be irritating to human skin and eyes and the user should be careful not to apply it to himself or other persons. Operators should wear rubber gloves and boots with a waterproof coat when applying the product. Protective clothing should be washed after use. As absorption through skin can occur, in the event of accidental skin contact the affected area should be washed immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water and seek medical attention. Do not eat, drink or smoke whilst handling the product. Wash hands after use. Use only in well-ventilated areas or outdoors.