For cattle and pigs the dose is 1 ml per 16kg bodyweight daily by intramuscular or slow intravenous injection.

Trimacare 24% may be administered by intravenous injection when rapid blood levels of sulfadiazine and trimethoprim are required.

For horses the dose is 1 ml per 16 kg bodyweight by slow intravenous injection.

For dogs and cats the dose is 1 ml per 8 kg bodyweight, by subcutaneous injection only. The recommended site in dogs is the loose skin at the top of the neck.

A single injection may be sufficient in uncomplicated conditions, but in severe infections they may be repeated daily until two days after the symptoms resolve, up to a maximum of five days.

An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.