Xylacare 2% solution is given by intramuscular injection taking precautions against contamination. The dose rate is 0.05-0.3 mg/kg xylazine (0.25 to 1.5 ml Xylacare 2% per 100kg bodyweight), according to the degree of sedation required. Very fractious animals may require higher dosage rates not exceeding 0.3 mg/kg (Dose rate 4).

Xylacare 2% is given by slow intravenous injection. Dosage depends upon the degree of sedation required and the response of the animal and is 0.6-1 mg/kg (3-5 ml/100 kg) bodyweight. Nervous or excitable horses may require higher doses. Older horses and those having undergone severe physical exertion before treatment should receive the lowest dose rate. The horse does not usually become recumbent with Xylacare 2% and light to deep sedation with variable degree of analgesia is obtained. Effects are usually seen within 5 minutes and persist for approximately 20 minutes. Xylacare 2% may be employed in the horse as a premedication to barbiturate anaesthesia or in combination with regional or local anaesthesia.

Xylacare 2% is administered intramuscularly at dose rates of 1-3 mg/kg (0.05-0.15 ml/kg bodyweight). It may be used in combination with a local anaesthetic. Premedication with atropine may be desirable in some cases. Xylacare 2% is synergistic with the barbiturates and reduces the dosage of the latter by approximately one half.

Xylacare 2% is administered intramuscularly at a dose rate of 3 mg/kg (0.15 ml/kg bodyweight). Premedication with atropine may occasionally be desirable.