Please refer to Table 1.

The recommended minimum dose is:

10 mg/kg bodyweight (bw) imidacloprid and 50 mg/kg bw permethrin.

To reduce re-infestation from emergence of new fleas it is recommended that all dogs in a household be treated. Other pet animals living in the same household should also be treated with a suitable product. To further aid in reducing environmental challenge, the additional use of a suitable environmental treatment against adult fleas and their developmental stages is recommended.

The product remains effective if the animal becomes wet. However, prolonged, intense exposure to water should be avoided. In cases of frequent water exposure the duration of activity may be reduced. In these cases do not re-treat more frequently than once weekly. If the dog requires shampooing, it is better to do so before applying Advantix or at least two weeks after application so as to ensure satisfactory efficacy of the product. Refer to the dosage table.

For dermal use only.

Remove one pipette from the package. Hold pipette in an upright position, twist and pull cap off. Turn the cap around and place the other end of the cap back on the pipette. Twist cap to break seal, then remove cap from pipette. See figure 1.

The dog should be standing for easy application.

Apply only to undamaged skin.

Part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin. See figure 2.

The entire contents of the Advantix® pipette(s) should be applied evenly to four spots on the midline of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the pipette on the skin and gently squeeze to expel a portion of the solution onto the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. See figure 3.

The product may be used during pregnancy and lactation.