Do not use on cats.

This product is extremely poisonous to cats and could be fatal due to the unique physiology of this species which is unable to metabolise certain compounds, including permethrin. To prevent cats from being accidentally exposed to the product, keep cats away from treated dogs until the application site is dry. It is important to ensure that cats do not groom the site of application on a dog which has been treated with this product. Seek veterinary advice immediately if this occurs.

In the absence of available data, the product should not be used on puppies of less than 7 weeks of age.

Each product also has a minimum weight limit:

Do not use in cases of known hypersensitivity to the active substances.

Care should be taken to avoid the contents of the pipette coming into contact with the eyes or mouth of the recipient dog.

Care should be taken to administer the product correctly as described above, under Method of Administration. In particular, oral uptake due to the licking of the application site by treated or in-contact animals should be avoided.

Consult your veterinary surgeon before using the product on sick and debilitated dogs.

On rare occasions, reactions in dogs may include transient skin sensitivity (including increased pruritus, alopecia and erythema at the application site) or lethargy.

Poisoning following inadvertent oral uptake in dogs is unlikely but may occur in very rare cases. In this event, neurological signs such as tremor and lethargy can occur. Treatment should be symptomatic under veterinary medical attention. There is no known specific antidote.

There may be an attachment of single ticks or bites by single sand flies or mosquitoes. For this reason, a transmission of infectious diseases by these parasites cannot be completely excluded if conditions are unfavourable.

Avoid contact between the product and skin, eyes or mouth.

Do not eat, drink or smoke during application.

Wash hands thoroughly after use.

In case of accidental spillage on human skin, wash off immediately with soap and water.

People with known skin sensitivity may be particularly sensitive to this product.

If the product gets accidentally into the eyes, they should be thoroughly flushed with water.

If skin or eye irritation persists, or if the product is accidentally swallowed, obtain medical attention immediately and show the package insert to the physician.

Treated dogs should not be handled, especially by children, until the application site is dry. This may be ensured by treating dogs when children are not present, eg in the evening after children have gone to bed. In this case, recently treated dogs should not be allowed to sleep together with their owner, especially children.

After use, replace cap on tube. Any unused product or waste material should be disposed of in accordance with national requirements.

Advantix® Spot-on should not be allowed to enter water courses as this may be dangerous for fish and aquatic organisms.

The product is dangerous to aquatic organisms. Do not, under any circumstances, allow treated dogs to enter any type of surface water, such as ponds, for at least 48 hours after treatment.

Permethrin containing products are toxic to honey bees.