Horsemeat and offal withdrawal period: 34 days. Not permitted for use in mares producing milk for human consumption.

Some horses carrying heavy infection of Onchocerca microfilaria have experienced oedema and pruritus following dosing, assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.

Avermectins may not be well tolerated in all non target species. Cases of intolerance are reported in dogs, especially Collies, Old English Sheepdogs and related breeds or crosses, and also in turtles and tortoises.

The product has been formulated specifically for use in horses only. Dogs and cats may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.

As ivermectin is extremely dangerous to fish and aquatic life treated animals should not have direct access to surface waters and ditches during treatment.

Parasite resistance to any particular class of anthehelminthic may develop following frequent, repeated use of an anthehelminthic of that class.

Horses of all ages, including pregnant mares and breeding stallions, have been treated with no adverse effect. When administering to lactating females, residues of ivermectin could be present in the maternal milk, since no studies have been reported on the development of new born horses of the ingestion of this milk, it would be prudent not to feed very young animals with milk obtained from the mother.

Mild transitory signs (slowed pupillary light response and depression) have been seen at a dose of 1.8mg/kg (9 times the recommended dose level). Other signs seen at higher doses includes mydriasis, ataxia, tremors, stupor, coma and death. The less severe signs have been transitory. No antidote has been identified; however, symptomatic therapy may be beneficial.

Do not eat, drink or smoke while handling the product. Avoid contact with skin and eyes. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water and, if necessary, get medical attention.

Wash hands after use.

EXREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used containers.