Introduction

vet06001

Company name: Bimeda

Address: A division of Cross Vetpharm Group UK Limited

Bryn Cefni Industrial Park,

Llangefni,

Anglesey LL77 7XA.

Telephone: 0800 526769

Fax: 01248 725416

Email: sales@bimeda.co.uk

Presentation

A yellow, gel-like oral paste of uniform consistency, containing 18.7 mg/g Ivermectin and 20 mg/g Apple Flavouring.

Uses

Bimectin is indicated for the treatment of parasitic infestations in horses due to:

Large Strongyles

Strongylus vulgaris (adults and 4th larval [arterial] stages), S. edentatus (adults and 4th larval [tissue] stages), S. equinus (adults)

Small Strongyles

Adults and immatures (fourth stage larvae) small strongyles or cyathostomes unless otherwise stated. Ivermectin is not effective against the encysted larval stages of the small strongyles

Triodontophorus spp. (adults); Triodontophorus brevicauda, Triodontophorus serratus.

Coronocyclus spp.; Coronocyclus coronatus, Coronocyclus labiatus, Coronocyclus labratus.

Cyathostomum spp.; Cyathostomum catinatum, Cyathostomum pateratum; Cylicocyclus spp.; Cylicocyclus ashworthi, Cylicocyclus elongatus, Cylicocyclus insigne, Cylicocyclus leptostomum, Cylicocyclus nassatus, Cylicocyclus radiatus.

Cylicostephanus spp.; Cylicostephanus asymetricus, Cylicostephanus bidentatus, Cylicostephanus calicatus, Cylicostephanus goldi, Cylicostephanus longibursatus, Cylicostephanus minutus.

Cylicodontophorus spp.; Cylicodontophorus bicornatus.

Gyalocephalus capitatus.

Parapoteriostomum spp.; Parapoteriostomum euproctus, Parapoteriostomum mettami.

Petrovinema spp.; Petrovinema poculatum.

Poteriostomum spp.; Poteriostomum imparidentatum.

Lungworms (adult and immatures)

Dictyocaulus arnfieldi

Pinworms (adult and immatures)

Oxyuris equi

Ascarids (adults and third & fourth stage larvae)

Parascaris equorum

Hairworms (adults)

Trichostrongylus axei

Large-mouth stomach worms (adults)

Habronema muscae

Neck threadworms (microfilariae)

Onchocerca spp.

Intestinal threadworms (adults)

Strongyloides westeri

Stomach bots

Oral and gastric stages of Gasterophilus spp.

Dosage and administration

Administer orally as a single dose rate to horses at the recommended dose level of 0.2mg ivermectin per kg of bodyweight. Each syringe delivers 120mg ivermectin, sufficient to treat 600kg of bodyweight.

Single administration. Bodyweight and dosage should be accurately determined prior to treatment.

Dosing instructions:

Each weight marking on the syringe plunger will deliver sufficient paste to treat 100kg bodyweight. Unlock the knurled ring by making ¼ turn and slide the knurled ring up the plunger shaft so that the side nearest the barrel is at the prescribed weight marking. Turn the knurled ring ¼ turn to lock in place. Make sure the horse’s mouth contains no feed. Remove the plastic cap from the tip of the nozzle. Insert the syringe into the horse’s mouth at the interdental space. Advance the plunger as far as it will go, depositing the medication on the base of the tongue. Immediately raise the horse’s head for a few seconds after dosing.

The treatment schedule should be based on the local epidemiological situation.

Contra-indications, warnings, etc

Horsemeat and offal withdrawal period: 34 days. Not permitted for use in mares producing milk for human consumption.

Some horses carrying heavy infection of Onchocerca microfilaria have experienced oedema and pruritus following dosing, assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.

Avermectins may not be well tolerated in all non target species. Cases of intolerance are reported in dogs, especially Collies, Old English Sheepdogs and related breeds or crosses, and also in turtles and tortoises.

The product has been formulated specifically for use in horses only. Dogs and cats may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.

As ivermectin is extremely dangerous to fish and aquatic life treated animals should not have direct access to surface waters and ditches during treatment.

Parasite resistance to any particular class of anthehelminthic may develop following frequent, repeated use of an anthehelminthic of that class.

Use during pregnancy and lactation

Horses of all ages, including pregnant mares and breeding stallions, have been treated with no adverse effect. When administering to lactating females, residues of ivermectin could be present in the maternal milk, since no studies have been reported on the development of new born horses of the ingestion of this milk, it would be prudent not to feed very young animals with milk obtained from the mother.

Overdose

Mild transitory signs (slowed pupillary light response and depression) have been seen at a dose of 1.8mg/kg (9 times the recommended dose level). Other signs seen at higher doses includes mydriasis, ataxia, tremors, stupor, coma and death. The less severe signs have been transitory. No antidote has been identified; however, symptomatic therapy may be beneficial.

Handling the product

Do not eat, drink or smoke while handling the product. Avoid contact with skin and eyes. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water and, if necessary, get medical attention.

Wash hands after use.

EXREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used containers.