All materials used in administering the vaccine must be free of antimicrobials, detergent or disinfectant residues to prevent inactivation.

10 and 50 dose presentation: Reconstitute the vaccine by adding the full content of the accompanying diluent to the vaccine. Shake well and use immediately.

100 dose presentation: Reconstitute the vaccine by adding half of the content of the accompanying diluent to the vaccine. Shake well and transfer the suspension back into the diluent bottle, mix with the remaining diluent to make up the full amount of 200 ml. Shake well and use immediately.

Administer a single 2 ml dose orally to pigs (from three weeks of age), irrespective of body weight.

Vaccination via the drinking water:

Water systems have to be cleaned and rinsed with untreated water to eliminate residues of antimicrobials, detergents or disinfectants. The final solution containing the vaccine should be consumed within four hours after preparation. Calculate the number of vials required to vaccinate all the pigs according to the table below:

Dilute the vaccine in the drinking water which will be consumed during a four hour time period. This should be calculated on the basis of the water intake observed during a four hour period at the time of planned vaccination on the previous day. Pigs will generally drink 8 to 12% of their body weight per day, depending on environmental temperatures. The actual amount of water consumed may vary considerably depending on several factors. It is essential for the efficacy of the product that pigs receive at least the recommended dose.

It is recommended to add skimmed milk powder or sodium thiosulfate solution as a stabiliser into the drinking water prior to adding the vaccine. The final concentration of the skimmed milk powder should be 2.5g/litre The final concentration of sodium thiosulfate should be approximately 0.055g/l.

After filling of the calculated water amount into the trough, sodium thiosulphate or skimmed milk powder should be added to the water. Afterwards, the vaccine is to be diluted either in the water / skimmed milk or in the water / thiosulphate mixture in the trough.