In common with other sedatives of this class, defensive movements, i.e. kicking may occur even in apparently well sedated animals. These occurrences may be reduced by the use of opiates, e.g. butorphanol.

As with other drugs of this class the administration of Sedivet may cause bradycardia, which may be profound, benign reversible cardiac arrhythmia with second degree heart block and hypotension. These effects may be prevented by the administration of 0.01 mg/kg atropine 5 minutes prior to administration of Sedivet. These effects are usually well-tolerated but care should be taken in patients with cardiovascular disease. Incoordination of the limbs and sweating may also occur.

When used as a pre-anaesthetic agent, sedation should be apparent before the induction of anaesthesia.

The concurrent i.v. use of potentiated sulphonamides with alpha2-agonists has been reported to cause cardiac arrhythmias which may be fatal. Whilst no such effects have been reported with Sedivet it is recommended that i.v. administration of TMP/S containing products should not be undertaken when horses have been sedated with Sedivet.

Animals must not be slaughtered for human consumption during treatment. Horses may be slaughtered for human consumption only after 6 days from the last treatment.

When used in combination with other products, consult the product literature of the products and apply whichever is the longer. However, if any of these products is contra-indicated for human consumption, then treated animals must not be slaughtered for human consumption.

Hyperglycaemia and diuresis may accompany sedation.

Sedivet should not be used in horses in the last month of pregnancy.

Sedivet is an alpha-2 adrenergic agonist. Wash off splashes from skin and eyes. Care should be taken to avoid accidental self injection. In the event of accidental self administration seek medical advice and show the label and other product literature, but do not drive as changes in blood pressure may be seen.

Unused product and containers should be disposed of in accordance with national requirements.

Keep out of the reach and sight of children.

For animal use only.