Introduction

Company name: Boehringer Ingelheim Limited

Address: Ellesfield Avenue

Bracknell

Berkshire RG12 8YS

Telephone: Sales & Marketing Enquiries 01344 746959

Telephone: Technical Enquiries 01344 746957

Fax: 01344 741349

Presentation

White to off-white granules for oral administration. Each aluminium foil sachet contains 37.5 g of product containing Trimethoprim 6.67% w/w and Sulphadiazine 33.33% w/w.

Uses

For the treatment of bacterial infections in horses.

Equitrim is a broad spectrum antibacterial; active against a wide range of Gram-positive and Gram-negative organisms. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria resulting in a level of activity much greater than that obtained from either drug alone.

In vitro Equitrim is effective against Escherichia coli, Corynebacterium equi, Staphylococcus spp., and Streptococcus spp. When susceptible organisms are present Equitrim Granules may be effective in treating the following conditions: Respiratory tract infections including pneumonia, pleurisy and strangles; Alimentary tract infections including diarrhoea; Wounds, septicaemia and general infections.

Dosage and administration

The daily dose is 30 mg combined active ingredients per kg bodyweight (25 mg sulphadiazine and 5 mg trimethoprim per kg bodyweight). Treatment should be continued for up to 5 days or until 2 days after symptoms have resolved.

Weight of	Daily Dose	Number of
Equitrim Granules	Bodyweight	scoops
7.5 g	100 kg	½
15 g	200 kg	1
22.5 g	300 kg	1½
30 g	400 kg	2
37.5 g	500 kg	whole sachet

Each sachet contains one daily dose for a 500 kg horse.

After careful estimation of the weight of the horse, the required dose of Equitrim Granules should be mixed well with the horse's feed prior to administration. A scoop, which gives 15 g when level, is provided.

Contra-indications, warnings, etc

Withdrawal Period: Not to be used in horses intended for human consumption. Treated horses may never be slaughtered for human consumption. The horse must have been declared as not intended for human consumption under national horse passport legislation.

Do not use in horses with known sulphonamide sensitivity, with hepatic damage, or with blood dyscrasias.

Avoid inhalation and direct contact with skin. Wash hands after use.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

The use of trimethoprim-sulphadiazine combinations during pregnancy and lactation has not been shown to cause any adverse effects or foetal abnormalities.

Keep out of the reach and sight of children.

For animal treatment only

Pharmaceutical precautions

Store below 25°C.

Any unused drug in open sachets remaining after the course of treatment should be discarded.

Legal category

POM-V

Packaging Quantities

Cartons of 100 sachets, each sachet containing 37.5 g of Equitrim Granules.

Further information

Nil.

Marketing authorisation number

Vm 00015/4044.