Prostaglandins of the F2α type can be absorbed through the skin and may cause bronchospasm or miscarriage.

Care should be taken when handling the product to AVOID SELF-INJECTION OR SKIN CONTACT.

Women of child-bearing age, asthmatics and persons with bronchial or other respiratory problems should avoid contact with, or wear disposable plastic gloves when administering the product.

Accidental spillage on the skin should be washed off immediately with soap and water.

Localised post injection bacterial infections that may become generalised have been reported. Aggressive antimicrobial therapy should be employed at the first sign of infection. Careful aseptic techniques should be employed to decrease the possibility of post injection bacterial infections.

Animals should not be treated if they suffer from either acute or sub-acute disorders of the vascular system, gastro-intestinal tract or respiratory system.

Pregnancy status should be determined prior to injection since Enzaprost® has been demonstrated to result in abortion or parturition induction when administered at sufficiently high doses to many animal species.

Do not administer by the intravenous route.

Enzaprost® is ineffective when administered prior to day five after ovulation.

If pregnant, the unlikely possibility of uterine rupture should be borne in mind, especially if cervical dilation does not occur.

Induction of parturition in pigs earlier than 72 hours prior to predicted farrowing date may result in reduced piglet viability.

For animal treatment only. Keep out of reach and sight of children.

Cattle: The most frequently observed side-effect is increased rectal temperature at a 5x or 10x overdose. However, rectal temperature changes have been transient in all cases observed and have not been detrimental to the animal. Limited salivation has been seen in some instances.

Pigs: Transient side-effects consisting of increased body temperature, increased respiratory rate, increased salivation, stimulation of defecation and urination, flushing of the skin and restlessness (arching of back, pawing, and rubbing and gnawing the crate) occur occasionally following the administration of dinoprost in pregnant sows and gilts. These effects tend to parallel the signs exhibited by sows prior to normal parturition, only they appear to be condensed in time. These effects are usually seen within 15 minutes of injection and disappear within one hour.

Animals must not be slaughtered for human consumption during treatment.

Cattle may be slaughtered for human consumption only after 3 days since last treatment.

Pigs may be slaughtered for human consumption only after 2 days since last treatment.

It is unnecessary to discard milk for human or animal consumption.