Prilactone tablets for dogs Dosage and administration For oral administration. 2 mg of spironolactone per kg of bodyweight once day. The product should be administered with food. Dosage Guide: Prilactone tablets for dogs Number of tablets Body weight (kg) 10 mg 40 mg 80 mg 1 to 2.5 ½ 2.5 to 5 1 5 to 10 2 10 to 15 3 15 to 20 1 20 to 30 1½ 30 to 40 1 40 to 50 1¼ 50 to 60 1½