Prilenal® tablets for dogs should be administered orally at the recommended dose of 0.5 mg/kg of enalapril maleate per day (i.e. 0.38 mg/kg of enalapril base per day). Individual doses should be administered based on body weight using the most appropriate tablet size or combination of tablets. The dosage can be adapted according to the clinical response of the treated animal. In the absence of expected clinical response within 2 weeks following initiation of the therapy, the dose of 0.5 mg/kg of enalapril maleate can be administered twice a day. The increase in dose can be more rapid if the signs of heart failure require it. Dogs should be observed closely for 48 hours following initial dosing or an increase in dose.