Albex 2.5% w/v SC Oral Suspension

Introduction

Chanelle Vet UK Ltd

Address: Chanelle Group

1st Floor, Freemans House

127 High Street, Hungerford

Berkshire, RG17 ODL

Telephone: 01908 843636

Fax: 01908 847401

Website: www.chanellegroup.com

 

Company name: Chanelle Animal Health Limited

7 Rodney Street

Liverpool

L1 9HZ

Tel & Fax: 01568 750432

Website: www.chanellegroup.ie

Presentation

A pale green free flowing suspension for oral administration. Each ml contains 25 mg Albendazole. Each ml also contains 0.27 mg selenium (as sodium selenite and 0.63 mg cobalt (as cobalt sulphate).

Uses

Albex 2.5% SC is a broad spectrum multi-purpose anthelmintic for the control of mature and developing immature forms of gastro-intestinal roundworms, lungworms, tapeworms and adult liver fluke in sheep and cattle. The product is also ovicidal against fluke and roundworm eggs. The selenium and cobalt in this product are trace elements of use as nutritional supplements.

In sheep it is active against benzimidazole-susceptible strains of the following species:

Roundworms: Ostertagia, Haemonchus, Trichostrongylus, Nematodirus (including N. battus), Chabertia and Oesophagostomum. It is usually effective against inhibited larvae of Ostertagia. Lungworms: Dictyocaulus filaria. Tapeworms: Moniezia spp. Adult liver fluke: Fasciola hepatica.

In cattle it is active against the following species:

Roundworms: Ostertagia, Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Bunostomum, Cooperia, and Strongyloides spp. It is usually effective against inhibited larvae of Cooperia and Ostertagia. Lungworms: Dictyocaulus viviparus. Tapeworms: Moniezia spp. Adult liver fluke: Fasciola hepatica.

Albex 2.5% SC is ovicidal and will kill fluke and roundworm eggs, thus reducing pasture contamination.

Dosage and administration

For oral administration only. To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked. Estimate bodyweight accurately.

Sheep

For the control of roundworms, lungworms, tapeworms and fluke and roundworm eggs, 5 mg albendazole per kg bodyweight which is equivalent to 2.0 ml Albex 2.5% SC per 10 kg bodyweight.

For the additional treatment of adult liver fluke (chronic fascioliasis) in sheep, 7.5 mg albendazole per kg bodyweight, which is equivalent to 3 ml Albex 2.5% SC per 10 kg bodyweight.

Dosage Guide Sheep

Bodyweight

Worm dose

(5.0 mg/kg)

Fluke & worm

(7.5 mg/kg)

Up to 10 kg

 2 ml

 3 ml

11–20 kg

 4 ml

 6 ml

21–30 kg

 6 ml

 9 ml

31–40 kg

 8 ml

12 ml

41–50 kg

10 ml

15 ml

51–60 kg

12 ml

18 ml

61–70 kg

14 ml

21 ml

71-80 kg

16 ml

24 ml

Sheep over 80 kg - give a further 2 or 3 ml for each additional 10 kg bodyweight.

Cattle

For the control of roundworms, lungworms, tapeworms and fluke and roundworm eggs, 7.5 mg albendazole per kg bodyweight which is equivalent to 15 ml Albex 2.5% SC per 50 kg bodyweight.

For the additional treatment of adult liver fluke (chronic fascioliasis) in cattle, 10 mg albendazole per kg bodyweight, which is equivalent to 20 ml Albex 2.5% SC per 50 kg bodyweight.

Dosage Guide Cattle

Bodyweight

Worm dose

(7.5 mg/kg)

Fluke & worm

(10 mg/kg)

 50 kg

 15 ml

 20 ml

100 kg

 30 ml

 40 ml

150 kg

 45 ml

 60 ml

200 kg

 60 ml

 80 ml

250 kg

 75 ml

100 ml

300 kg

 90 ml

120 ml

350 kg

105 ml

140 ml

400 kg

120 ml

160 ml

Cattle over 400 kg - give a further 15 or 20 ml for each additional 50 kg bodyweight.

Contra-indications, warnings, etc

Do not use in animals with known hypersensitivity to the active ingredient.

Do not dose ewes at the `fluke and worm dose' (7.5 mg/kg) during tupping or for 1 month after removing the rams. Can be safely used during lactation.

Do not administer other cobalt and selenium supplements concurrently with this product unless specifically advised by your veterinary surgeon.

Withdrawal periods

Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 14 days from the last treatment. Milk for human consumption may be taken from cows only after 60 hours from the last treatment. Sheep may be slaughtered for human consumption only after 5 days from the last treatment. Do not use in sheep producing milk for human consumption.

Operator warnings

Avoid direct contact with the product. Wash hands after use.

Wear suitable protective clothing including impermeable rubber gloves. In the event of accidental eye exposure, flush eye thoroughly with running water. If irritation persists, seek medical attention. In the event of accidental skin exposure, wash the affected area with soap and water. If irritation persists, seek medical attention.

Environmental warnings

DANGEROUS to fish and aquatic life. Do not contaminate ponds, waterways or ditches with product or used containers. Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements

General precautions

For animal treatment only. Keep out of the reach of children. Assess bodyweight as accurately as possible before calculating the dosage. Care must be taken not to damage the pharyngeal region, particularly in sheep, when dosing.

Intensive use or misuse of anthelmintics can give rise to resistance. To reduce this risk, dosing programmes should be discussed with your Veterinary Surgeon.

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:

- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.

- Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to benzimidazoles (which includes albendazole) has been reported in Teladorsagia Haemonchus, Cooper and Trichostrongylus species in small ruminants in a number of countries, including the EU. Resistance to albendazole has been reported in Cooperia and Teladorsagia species in cattle in developed countries such as New Zealand. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

Pharmaceutical precautions

Shake container before use. Avoid the introduction of contamination during use. Do not mix with other products.

Packaging Quantities

1 L, 2.5 L, 5 L and 10 L.

Legal category

POM-VPS

Further information

Selenium and cobalt are included in Albex 2.5% SC as nutritional supplements and are not intended to be used therapeutically. Administration of ionophores to lambs has been shown to enhance selenium bioavailability. Concurrent administration of ionophores and Albex 2.5% SC may therefore lead to an increased risk of selenium toxicity.

The use of Albex 2.5% SC in breeding bulls or pregnant cattle is not expected to interfere with their reproductive performance. Cattle suffering from severe lung damage due to heavy lungworm infestation may continue to cough for some weeks after treatment. The product should only be used in areas where deficiencies of selenium and cobalt are likely to occur. In cases of doubt, consult a veterinary surgeon.

Marketing authorisation number

Vm 11990/4015.