NOAH Compendium of Animal Medicines: Atipam 5.0 mg/ml Solution for Injection for Cats and Dogs

Atipam 5.0 mg/ml Solution for Injection for Cats and Dogs

Dosage and administration

For single intramuscular injection in cats and dogs. Use of an appropriately graduated syringe is recommended to ensure accurate dosing when administering small volumes. Atipamezole is generally administered 15 - 60 minutes after the medetomidine or dexmedetomidine injection.

Dogs: The atipamezole hydrochloride dose (in µg) is five times that of the previous medetomidine hydrochloride dose or ten times that of the dexmedetomidine hydrochloride dose. Due to the 5-fold higher concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml, and the 10-fold higher concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, an equal volume of each preparation is required.

Dosage example dogs:

Medetomidine 1.0 mg/ml solution for injection Dosage:	Atipam 5.0 mg/ml solution for injection Dosage:
0.04 ml/kg body weight (bw), i.e. 40 µg/kg bw	0.04 ml/kg bw, i.e. 200 µg/kg bw
Dexmedetomidine 0.5 mg/ml solution for injection Dosage:	Atipam 5.0 mg/ml solution for injection Dosage:
0.04 ml/kg body weight (bw), i.e. 20 µg/kg bw	0.04 ml/kg bw, i.e. 200 µg/kg bw

Cats: The atipamezole hydrochloride dose (in µg) is 2.5 times that of the previous medetomidine hydrochloride dose, or 5 times that of the dexmedetomidine hydrochloride dose. Due to the 5-fold higher concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml, and the 10-fold higher concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, half the volume of the product to that of the previously administered medetomidine or dexmedetomidine should be given.

Dosage example cats:

Medetomidine 1.0 mg/ml solution for injection Dosage:	Atipam 5.0 mg/ml solution for injection Dosage:
0.08 ml/kg body weight (bw), i.e. 80 µg/kg bw	0.04 ml/kg bw, i.e. 200 µg/kg bw
Dexmedetomidine 0.5 mg/ml solution for injection Dosage:	Atipam 5.0 mg/ml solution for injection Dosage:
0.08 ml/kg body weight (bw), i.e. 40 µg/kg bw	0.04 ml/kg bw, i.e. 200 µg/kg bw

The recovery time is shortened to approximately 5 minutes. Animals become mobile after approximately 10 minutes after administration of the product.

Advice on correct administration: In the absence of compatibility studies this veterinary medicinal product must not be mixed with other veterinary medicinal products in the same syringe.