Frusedale 40 mg Oral Tablets Uses Frusedale 40 mg oral tablets are for use in cats and dogs only, for the treatment of oedema associated with cardiac insufficiency, renal dysfunction and trauma. In animals with pulmonary oedema of cardiac origin, combined therapy with other medicinal products may be indicated. Frusemide is a potent diuretic with an onset of activity normally within 1 hour of administration and a duration of activity of approximately 4 hours.