Intra-Epicaine 2.0 % w/v Solution for Injection Uses Mepivacaine Hydrochloride is a potent local anaesthetic, with a rapid onset of action. Since it does not cause vasodilation it does not require adrenaline to prolong its effect. Mepivacaine has been employed successfully for all types of local anaesthesia and is recommended for infiltration, nerve block, intra-articular and epidural anaesthesia in horses.