Introduction

Dechra

Company name: Dechra Veterinary Products

Address: (A business unit of Dechra Pharmaceuticals PLC)

Cartmel Drive

Harlescott

Shrewsbury SY1 3TB

Telephone: 01743 441632

Fax: 01743 462111

Email: info@dechra-uk.com

Website: www.dechra-uk.com

Presentation

A clear, colourless, sterile, apyrogenic solution for intravenous infusion containing:

Glucose Monohydrate 5.5 % w/v

(equivalent to anhydrous Glucose 5.0 % w/v)

Water for injections to 100 % w/v

Each one litre provides approximately 200 kcal.

Uses

This product is administered by intravenous infusion for the treatment of dehydration (in the absence of shock) in cattle, calves, horses, dogs and cats. It is used to replace water when it cannot be taken or retained orally.

Glucose infusions are used to correct hypernatraemia (by replacing lost water) and hyperkalaemia (through the promotion of insulin production which in turn causes Potassium to move from plasma into cells). It is not a significant calorie source but can provide transient improvement of hypoglycaemia.

Dosage and administration

This product should be administered intravenously at a rate not exceeding 10 ml/kg/hour.

Maintain aseptic precautions.

DIRECTIONS FOR USE

VISUAL INSPECTION

1. Ensure that the solution is clear and free from particles, and that the container is undamaged (check for leaks). If you regard the integrity of the pack as suspect, discard solution.

2. Read all precautionary notes (label and package leaflet) and check the expiry date before use.

PACK PREPARATION

1. Warm the pack to approximately 37°C.

2. Remove the pack from the protective overwrap by tearing downwards from the serrated edge.

3. Carefully straighten hanger and ports if necessary.

4. Remove the port plug protecting the sterile giving port. Do this by twisting off the top section while holding the bottom section.

5. Insert the administration set fully to produce a leak-proof connection and suspend the bag from an infusion stand.

6. An air inlet is not required.

7. Prime and regulate the administration set in accordance with the manufacturer’s instructions. If the administration set becomes blocked, do not pump solution back into the pack, replace equipment.

AFTER USE

1. The solution does not contain an antimicrobial preservative and is intended for single use only. Discard any unused solution.

2. Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Contra-indications, warnings, etc

This product should not be administered to hyperglycaemic animals.

This product should be used with care in diabetic patients.

A risk of thrombosis with intravenous infusion should be considered.

This product should not be administered at a rate in excess of 10 ml/kg/hour, otherwise glycosuria and osmotic diuresis may result. Furthermore, severe or long-standing hypernatraemia should be corrected gradually.

Adverse reactions: Monitor fluid output and blood Glucose.

Use under veterinary supervision during pregnancy and lactation or lay.

Incompatibility with certain antibiotics and Heparin are recognised.

Overdose: Monitor fluid output and blood Glucose.

General precautions: For animal treatment only.

Withdrawal period: Cattle meat - zero days.

Cattle milk - zero days.

Horse meat - zero days.

Pharmaceutical precautions

Do not store above 25°C. Do not freeze. Keep out of the reach and sight of children.

Shelf life: Do not use unless the solution is clear, free from visible particles and the container is undamaged.

Unopened: 2 years.

After opening: The product does not contain an antimicrobial preservative. It is intended for single use only and any unused contents should be discarded.

Disposal: Any unused product or waste material should be disposed of in accordance with national requirements.

Legal category

POM-V

Packaging Quantities

Presented in polyvinylchloride (PVC) infusion bags, overwrapped with polypropylene, in cartons of 20 x 500 ml and 10 x 1000 ml.

Not all pack sizes may be marketed.

Each carton contains sufficient number of package leaflets so that individual units may be supplied.

Further information

ATC Vet Code: QB05BB. Solutions affecting the electrolyte balance.

Pharmacodynamic properties: Glucose 5 % w/v Intravenous Infusion BP (Vet) is used as a replacement source of water and Glucose for animals who cannot be given rehydration fluids orally. It is temporarily isotonic (thereby avoiding causing osmotic shock to red blood cells), the Glucose is then metabolised leaving water. The Glucose can provide a transient source of nutrient and will aid in correction of a hyperkalaemia.

Pharmacokinetic properties: Intravenous infusion ensures rapid distribution. The constituents of the infusion solution will be metabolised and excreted through the same pathways as those substances derived from normal dietary sources.

To be supplied only on veterinary prescription.

UK authorised veterinary medicinal product.