The fluoroquinolones exert their antibacterial effect against both replicating and non replicating micro-organisms. Difloxacin hydrochloride is bactericidal in activity and acts by inhibition of bacterial DNA gyrase.

Strains of Escherichia coli, Pasteurella multocida, Mycoplasma gallisepticum isolated from broilers and turkeys have been shown to be sensitive to difloxacin.

Chickens (broilers and future breeders) and turkeys (young turkeys up to 2 Kg body weight).

In chickens and turkeys Dicural* oral solution is indicated for treatment of chronic respiratory infections caused by sensitive strains of Escherichia coli and Mycoplasma gallisepticum.

In turkeys Dicural* oral solution is also indicated for the treatment of infections caused by Pasteurella multocida.

Dicural* oral solution should only be used based on susceptibility testing.