Duphacillin is a broad-spectrum semi-synthetic penicillin, bactericidal in action, for use in cattle, sheep and pigs. In vitro it is effective against a wide range of Gram-positive and Gram-negative pathogenic bacteria including: Bordetella bronchiseptica, Arcanobacterium pyogenes, Erysipelothrix rhusiopathiae, Mannheimia haemolytica, Pasteurella multocida, Salmonella spp, non penicillinase producing Staphylococcus spp, and Streptococcus spp.

Duphacillin will therefore be effective in the treatment of infections caused by susceptible organisms including: erysipelas; navel/joint ill; respiratory tract infections, including pneumonia and atrophic rhinitis; meningitis; septicaemia; urogenital tract infections and the control of secondary bacterial invaders in diseases of primary viral origin.

Duphacillin will also have some effect in the treatment of enteritis caused by Salmonella species.