Oxytetracycline is a bacteriostatic antibiotic active against a wide range of Gram-positive and Gram-negative bacteria. Following intramuscular injection peak blood levels are achieved within 4 to 8 hours for the treatment of acute infections. Blood levels then persist for at least 4 days to give prolonged activity.

Duphacycline LA is indicated for the treatment and control of diseases caused by organisms sensitive to oxytetracycline in cattle, sheep and pigs. These include Bordetella bronchiseptica, Actinomyces pyogenes, Erysipelothrix rhusiopathiae, Escherichia coli, Haemophilus somnus, Pasteurella haemolytica, Pasteurella multocida, Salmonella dublin, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus faecalis, Streptococcus pyogenes and Streptococcus uberis.

Duphacycline LA is indicated in the treatment of atrophic rhinitis caused by Bordetella bronchiseptica, Pasteurella haemolytica and Pasteurella multocida. Navel/joint ill caused by Actinomyces pyogenes E. coli and Staphylococcus aureus. Mastitis caused by Actinomyces pyogenes, E. coli, Staphylococcus aureus, Streptococcus agalactiae and Streptococcus uberis. Metritis caused by E. coli and Streptococcus pyogenes. Pasteurellosis and infections of the respiratory tract caused by Pasteurella haemolytica and Pasteurella multocida. Septicaemia caused by Salmonella dublin and Streptococcus pyogenes. Erysipelas caused by Erysipelothrix rhusiopathiae.