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Duphatrim IS Injectable Solution
Contra-indications, warnings, etc
FOR ANIMAL TREATMENT ONLY
Injections should not be given by routes other than those recommended. Not to be administered
intraperitoneally.
Adequate drinking water should be available during the therapeutic effect of the product.
Do not administer to animals with known sulphonamide sensitivity, severe liver parenchymal damage, or blood dyscrasias. As with all Trimethoprim/Sulphonamide formulations the possibility of potential damage to the kidney or liver or haemapoeitic system should be considered.
Do not administer to horses exhibiting drug-induced cardiac arrhythmias. Such arrhythmias may be associated with the administration of certain anaesthetic and sedative agents. The intravenous route is contraindicated in the case of concurrent or previous administration of central nervous system depressants (e.g. anaesthetics, neuroleptics).
Intravenous injections should be at body temperature and administered slowly over as long a period as is reasonably practical in order to avoid possible anaphylactic shock. If intolerance develops, immediately interrupt the injection and initiate shock treatment.
The possibility of anaphylaxis should be considered and the intravenous route in the horse should only be used if therapeutically justified.
Withdrawal periods
Milk for human consumption must not be taken during treatment. Milk for human consumption may be taken from cows only after 48 hours from the last treatment.
Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 12 days from the last treatment. Pigs may be slaughtered for human consumption only after 20 days from the last treatment.
Not to be used in horses intended for human consumption.
The horse must have been declared as not intended for human consumption in accordance with the UK's Horse Passport Legislation.
Operator Warnings
Care must be taken to avoid accidental self-injection.
Avoid direct contact with skin and eyes. In the event of accidental spillage, wash affected area with copious amounts of water, seek medical advice if irritation persists.
Wash hands after use.
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