For the active immunisation of dogs to prevent mortality and disease caused by canine distemper virus and canine parvovirus, to prevent mortality and reduce clinical signs due to infectious canine hepatitis and Leptospira and to reduce clinical signs and infection caused by canine adenovirus 2 and to reduce shedding of canine parainfluenza virus.

The onset of immunity is from two weeks after the second vaccination. The duration of immunity is at least three years for the canine distemper virus, canine adenovirus and canine parvovirus fractions. The duration of immunity is at least one year for the leptospira fractions. The duration of immunity for the canine parainfluenza component is not known but may be less than a year.