Duramune DAPPi + LC is a combination vaccine presented as a lyophilisate and diluent for suspension for injection. Each dose comprises:

one vial of a freeze dried fraction containing live attenuated strains of canine distemper virus, strain Onderstepoort, (102.5 to 104.8 TCID50); canine adenovirus type 2, strain V197 (104.8 to 107.0 TCID50); canine parvovirus, strain SAH (104.7 to 106.5 TCID50) and canine parainfluenza virus (105.1 to 107.4 TCID50); and one vial of liquid diluent fraction, an inactivated adjuvanted suspension of canine coronavirus, strain TN449 (RP 1.0-2.0), Leptospira canicola outer membrane coat protein (potency as per Ph.Eur) and Leptospira icterohaemorrhagiae outer membrane coat protein (potency as per Ph.Eur).